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检索条件"机构=200025"
33207 条 记 录,以下是1-10 订阅
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Dynamic expression of proteins associated with adventitial remodeling in adventitial fibroblasts from spontaneously hypertensive rats
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Acta Pharmacologica Sinica 2010年 第10期31卷 1312-1318页
作者: Guo, Shu-jie Wang, Tai-rong Chen, Jing Wu, Ling-yun Gao, Ping-jin Zhu, Ding-liang Shanghai Jiao Tong Univ State Key Lab Med Genom Shanghai Key Lab Vasc Biol Sch Med Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Dept Hypertens Ruijin Hosp Sch Med Shanghai 200025 Peoples R China Chinese Acad Sci Shanghai Inst Biol Sci Lab Vasc Biol Inst Hlth Sci Shanghai 200025 Peoples R China Shanghai Res Inst Hypertens Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Luwan Branch Ruijin Hosp Sch Med Shanghai 200025 Peoples R China
Aim: To identify proteins that could potentially be involved in adventitial remodeling in vascular adventitial fibroblasts (AFs) from spontaneously hypertensive rats (SHR). Methods: AFs were isolated from thoracic aor... 详细信息
来源: nature期刊(calis) nature期刊(calis) ebsco(MEDLINE/cmedm) 评论
Adaptive changes in autophagy after UPS impairment in Parkinson's disease
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Acta Pharmacologica Sinica 2013年 第5期34卷 667-673页
作者: Shen, Yu-fei Tang, Yu Zhang, Xiao-jie Huang, Kai-xing Le, Wei-dong Jiao Tong Univ Sch Med Ruijin Hosp Inst Neurol Shanghai 200025 Peoples R China Chinese Acad Sci Shanghai Inst Biol Sci Inst Hlth Sci Key Lab Stem Cell Biol Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Shanghai 200025 Peoples R China
Aim: Ubiquitin-proteasome system (UPS) and autophagosome-lysosome pathway (ALP) are the most important machineries responsible for protein degradation in Parkinson's disease (PD). The aim of this study is to investiga... 详细信息
来源: nature期刊(calis) nature期刊(calis) 评论
New microbiota found in sputum from patients with community-acquired pneumonia
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Acta Biochimica et Biophysica Sinica 2013年 第12期45卷 1039-1048页
作者: Chen, Chunyan Shen, Tian Tian, Fei Lin, Ping Li, Qingtian Cui, Zelin Zhang, Yajuan Xue, Min Ye, Jing Guo, Xiaokui Zhou, Yuhua Shanghai Jiao Tong Univ Sch Med Dept Prevent Med Dept Med Microbiol & Parasitol Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Shanghai Mental Hlth Ctr Dept Med Lab Shanghai 200030 Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Lab Med Shanghai 200025 Peoples R China Shanghai Minhang Cent Hosp Dept Resp Shanghai 201100 Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Emergency Med Shanghai 200025 Peoples R China
Community-acquired pneumonia (CAP) is a major concern in hospitals and the bacterial community of which has not been systemically discussed yet. Sputum from patients in the acute stages is a kind of accessible sample ... 详细信息
来源: 牛津期刊现刊库 评论
Histone deacetylase inhibitors attenuate P-algA1-induced cell proliferation and extracellular matrix synthesis in human renal mesangial cells in vitro
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Acta Pharmacologica Sinica 2016年 第2期37卷 228-234页
作者: Dai, Qin Liu, Jian Du, Yun-lei Hao, Xu Ying, Ji Tan, Yun He, Li-qun Wang, Wei-ming Chen, Nan Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Nephrol Shanghai 200025 Peoples R China Cent Hosp Xuhui Dist Dept Nephrol Shanghai 200031 Peoples R China Punan Hosp Dept Nephrol Shanghai 200125 Peoples R China Shanghai Inst Hematol Shanghai 200025 Peoples R China Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol Shanghai 200021 Peoples R China
Aim: Aberrantly glycosylated IgA1 is a key factor in the pathogenesis of IgA nephropathy (IgAN). In this study we investigated the effects of aggregated IgA1 derived from IgAN patients (P-algA1) on human renal mesangi... 详细信息
来源: nature期刊(calis) nature期刊(calis) 评论
Four New Nortriterpenoids from Schisandra lancifolia
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Helvetica chimica acta 2010年 第10期93卷 1975-1982页
作者: Xiao, Wei-Lie Wu, Ying-Li Shang, Shan-Zhai He, Fei Luo, Xiao Yang, Guang-Yu Pu, Jian-Xin Chen, Guo-Qiang Sun, Han-Dong Chinese Acad Sci Kunming Inst Bot State Key Lab Phytochem & Plant Resources W China Kunming 650204 Peoples R China Chinese Acad Sci Dept Pathophysiol Shanghai 200025 Peoples R China Chinese Acad Sci Key Lab Cell Differentiat & Apoptosis Shanghai 200025 Peoples R China Chinese Acad Sci Grad Sch Beijing 100039 Peoples R China
Four new highly oxygenated nortriterpenoids, lancifodilactones O-R (1-4), together with six known ones, i.e., 5-10, were isolated from the leaves and stems of Schisandra lancifolia. Their structures were elucidated by... 详细信息
来源: Wiley期刊 Wiley期刊 EBSCOASC期刊 EBSCOASC期刊 评论
MicroRNA or NMD: Why Have Two RNA Silencing Systems?
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Journal of genetics and genomics 2013年 第10期40卷 497-513页
作者: Zhang, Zhenguo Hu, Landian Kong, Xiangyin Penn State Univ Inst Mol Evolutionary Genet University Pk PA 16802 USA Penn State Univ Dept Biol University Pk PA 16802 USA Chinese Acad Sci Shanghai Inst Biol Sci Inst Hlth Sci Key Lab Stem Cell Biol Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Shanghai 200025 Peoples R China
MicroRNA (miRNA)-mediated RNA silencing and nonsense-mediated decay (NMD) are two conserved RNA-level regulatory pathways. Although they are mechanically different, both can regulate target genes by RNA degradation an... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... ebsco(MEDLINE/cmedm) 评论
Why should autophagic flux be assessed?
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Acta Pharmacologica Sinica 2013年 第5期34卷 595-599页
作者: Zhang, Xiao-jie Chen, Sheng Huang, Kai-xing Le, Wei-dong Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Inst Neurol Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Chinese Acad Sci Shanghai Inst Biol SciInst Hlth Sci Shanghai 200025 Peoples R China
As autophagy is involved in cell growth, survival, development and death, impaired autophagic flux has been linked to a variety of human pathophysiological processes, including neurodegeneration, cancer, myopathy, car... 详细信息
来源: nature期刊(calis) nature期刊(calis) ebsco(MEDLINE/cmedm) 评论
Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin
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Acta Pharmacologica Sinica 2009年 第9期30卷 1262-1275页
作者: Xie, Zuo-quan Liang, Gai Zhang, Lu Wang, Qi Qu, Yi Gao, Yang Lin, Li-bo Ye, Sai Zhang, Ji Wang, Hui Zhao, Guo-ping Zhang, Qing-hua Shanghai Jiao Tong Univ Sch Med Ruijin Hosp State Key Lab Med Genom Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Shanghai Inst Hematol Shanghai 200025 Peoples R China Natl Engn Ctr Biochip Shanghai 201203 Peoples R China Shanghai Biochip Co Ltd Shanghai 201203 Peoples R China Wuhan Univ Basic Med Sch Dept Pharmacol Wuhan 430071 Peoples R China Shanghai MOST Key Lab Hlth & Dis Genom Shanghai 201203 Peoples R China
Aim: To explore the molecular mechanisms underlying the cholesterol-lowering effect of a Ginkgo biloba extract (GBE). Methods: Enzyme activity, cholesterol flux and changes in gene expression levels were assessed in c... 详细信息
来源: nature期刊(calis) nature期刊(calis) ebsco(MEDLINE/cmedm) 评论
Regucalcin plays a role in the cytoskeleton regulation of HepG2 cells
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Acta Biochimica et Biophysica Sinica 2017年 第2期49卷 193-195页
作者: Chen, Jia Xu, Beihui Wu, Jiemin Liu, Xiangfan Xu, Hong Ni, Peihua Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Lab Med Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Ninth Peoples Hosp Dept Clin Lab Shanghai 200023 Peoples R China Shanghai Jiao Tong Univ Sch Med Dept Biochem & Mol Cell Biol Shanghai 200025 Peoples R China
来源: 牛津期刊现刊库 ebsco(MEDLINE/cmedm) 评论
Cloning and characterization of three cheB genes in Leptospira interrogans
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Acta Biochimica et Biophysica Sinica 2010年 第3期42卷 216-223页
作者: Dong, Ke Li, Qingtian Liu, Chang Zhang, Yunyi Zhao, Guoping Guo, Xiaokui Shanghai Jiao Tong Univ Sch Med Inst Med Sci Dept Microbiol & Parasitol Shanghai 200025 Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Lab Med Shanghai 200025 Peoples R China Chinese Acad Sci Shanghai Inst Biol Sci Inst Plant Physiol & Ecol Key Lab Synthet Biol Shanghai 200032 Peoples R China
Motility and chemotaxis systems are critical for the virulence of leptospires. There were multiple copies of putative chemotaxis homologs located at leptospires large chromosome. CheB1 and CheB3 from Leptospira interr... 详细信息
来源: 牛津期刊现刊库 评论