限定检索结果

文献类型

  • 256 篇 期刊文献
  • 7 篇 学位论文

馆藏范围

  • 263 篇 电子文献

日期分布

学科分类号

  • 74 篇 理学
    • 45 篇 生物学
    • 4 篇 海洋科学
    • 3 篇 化学
    • 1 篇 天文学
    • 1 篇 地理学
  • 72 篇 艺术学
    • 72 篇 音乐与舞蹈学
  • 53 篇 医学
    • 31 篇 药学(可授医学、理...
    • 17 篇 临床医学
    • 3 篇 公共卫生与预防医...
    • 1 篇 基础医学(可授医学...
  • 12 篇 哲学
    • 11 篇 哲学
  • 7 篇 工学
    • 2 篇 动力工程及工程热...
    • 1 篇 材料科学与工程(可...
    • 1 篇 电气工程
    • 1 篇 化学工程与技术
    • 1 篇 安全科学与工程
  • 5 篇 经济学
    • 5 篇 应用经济学
  • 3 篇 管理学
    • 3 篇 管理科学与工程(可...
  • 2 篇 法学
    • 2 篇 社会学
  • 1 篇 教育学
  • 1 篇 文学

主题

  • 52 篇 reviews
  • 24 篇 music
  • 14 篇 discovery
  • 13 篇 design
  • 11 篇 expression
  • 11 篇 instrumental mus...
  • 11 篇 orchestral music
  • 11 篇 potent
  • 10 篇 piano music
  • 10 篇 protein-kinase
  • 8 篇 hypertension
  • 8 篇 identification
  • 8 篇 intraocular-pres...
  • 7 篇 apoptosis
  • 7 篇 in-vitro
  • 7 篇 ligand
  • 6 篇 contemporary cla...
  • 6 篇 fasudil
  • 6 篇 jnk
  • 6 篇 kinase

机构

  • 26 篇 scripps res inst...
  • 20 篇 scripps res inst...
  • 10 篇 scripps res inst...
  • 9 篇 scripps florida,...
  • 9 篇 scripps res inst...
  • 8 篇 scripps florida,...
  • 8 篇 scripps res inst...
  • 7 篇 scripps florida,...
  • 6 篇 scripps florida,...
  • 6 篇 univ miami, ctr ...
  • 5 篇 scripps res inst...
  • 4 篇 dana farber canc...
  • 4 篇 dana farber canc...
  • 4 篇 scripps florida,...
  • 4 篇 scripps res inst...
  • 4 篇 scripps res inst...
  • 4 篇 univ calif san f...
  • 4 篇 univ calif san f...
  • 4 篇 univ miami, dept...
  • 4 篇 univ waikato, de...

作者

  • 111 篇 cameron, michael
  • 86 篇 cameron, michael...
  • 30 篇 lin, li
  • 28 篇 cameron, michael...
  • 25 篇 kamenecka, theod...
  • 19 篇 ruiz, claudia
  • 17 篇 cameron, michael...
  • 15 篇 feng, yangbo
  • 14 篇 bannister, thoma...
  • 14 篇 cameron, michael...
  • 14 篇 lograsso, philip
  • 12 篇 boveng, peter l.
  • 12 篇 song, xinyi
  • 11 篇 cameron, michael...
  • 11 篇 roush, william r...
  • 10 篇 chen, weimin
  • 10 篇 duckett, derek
  • 10 篇 grant, wayne
  • 10 篇 ruiz, claudia h.
  • 10 篇 schroeter, thoma...

语言

  • 262 篇 英文
  • 1 篇 中文
检索条件"作者=Cameron, Michael"
263 条 记 录,以下是1-10 订阅
排序:
Synthesis of Benzoquinone Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid
收藏 引用
Angewandte Chemie International Edition 2013年 第18期52卷 4800-4804页
作者: Jeso, Valer Iqbal, Sarah Hernandez, Pamela Cameron, Michael D. Park, HaJeung LoGrasso, Philip V. Micalizio, Glenn C. Scripps Res Inst Dept Chem Jupiter FL 33458 USA Scripps Res Inst Dept Mol Therapeut Jupiter FL 33458 USA
One is not like the other: The title approach proceeds by stepwise coupling of three relatively simple substrates. Three natural product-inspired agents are described, one of which has natural product-like toxicity fo... 详细信息
来源: Wiley期刊 Wiley期刊 ebsco(MEDLINE/cmedm) 评论
Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo
JCI insight
收藏 引用
JCI insight 2017年 第22期2卷
作者: Huang, Xi-Ping Che, Tao Mangano, Thomas J. Le Rouzic, Valerie Pan, Ying-Xian Majumdar, Susruta Cameron, Michael D. Baumann, Michael H. Pasternak, Gavril W. Roth, Bryan L. Univ N Carolina Sch Med Dept Pharmacol Chapel Hill NC USA NIMH Psychoact Drug Screening Program Chapel Hill NC USA Mem Sloan Kettering Canc Ctr Dept Neurol 1275 York Ave New York NY 10021 USA Mem Sloan Kettering Canc Ctr Mol Pharmacol Program 1275 York Ave New York NY 10021 USA Scripps Res Inst Dept Mol Therapeut Jupiter FL USA NIDA Intramural Res Program Designer Drug Res Unit NIH Baltimore MD USA
W-18 (4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]-2-piperidinylidene]-benzenesulfonamide) and W-15 (4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]-benzenesulfonamide) represent two emerging drugs of abuse chemically rel... 详细信息
来源: ebsco(MEDLINE/cmedm) 评论
The challenges and possible solutions of horizontal axis wind turbines as a clean energy solution for the future
收藏 引用
Renewable & sustainable energy reviews 2014年 38卷 439-460页
作者: Ahmed, Noor A. Cameron, Michael Univ New S Wales Sch Mech & Mfg Engn Sydney NSW 2052 Australia
This paper presents a review of existing and emerging wind power technologies in light of the evident trends of the industry, and describes the challenges these technologies will face if wind turbines were to become a... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... EBSCOASC期刊 EBSCOASC期刊 ebsco(ASP/aph) ebsco(GreenFILE/8gh) 评论
A multi-species synthesis of satellite telemetry data in the Pacific Arctic (1987-2015): Overlap of marine mammal distributions and core use areas
收藏 引用
Deep-sea research, Part II. Topical studies in oceanography 2018年 152卷 132-153页
作者: Citta, John J. Lowry, Lloyd F. Quakenbush, Lori T. Kelly, Brendan P. Fischbach, Anthony S. London, Josh M. Jay, Chadwick, V Frost, Kathryn J. Crowe, Gregory O'Corry Crawford, Justin A. Boveng, Peter L. Cameron, Michael Von Duyke, Andrew L. Nelson, Mark Harwood, Lois A. Richard, Pierre Suydam, Robert Heide-Jorgensen, Mads Peter Hobbs, Roderick C. Litovka, Dennis, I Marcoux, Marianne Whiting, Alex Kennedy, Amy S. George, John C. Orr, Jack Gray, Tom Alaska Dept Fish & Game 1300 Coll Rd Fairbanks AK 99701 USA Univ Alaska Sch Fisheries & Ocean Sci 73-4388 Paiaha St Kailua Kona HI 96740 USA Univ Alaska Int Arctic Res Ctr Fairbanks AK 99775 USA US Geol Survey Alaska Sci Ctr 4210 Univ Dr Anchorage AK 99508 USA Natl Marine Fisheries Serv Alaska Fisheries Sci Ctr Marine Mammal Lab 7600 Sand Point Way NE Seattle WA 98115 USA Florida Atlantic Univ Harbor Branch Oceanog Inst 5600 US 1 North Ft Pierce FL 34946 USA North Slope Borough Dept Wildlife Management POB 69 Utqiagvik AK 99723 USA Fisheries & Oceans Canada Yellowknife NT X1A 1E2 Canada Fisheries & Oceans Canada 501 Univ Crescent Winnipeg MB R3T 2N6 Canada Greenland Inst Nat Resources Strandgade 912 DK-1401 Copenhagen K Denmark ChukotTINRO Marine Mammal Lab Str Otke 56 Anadyr Chukotka 689000 Chukotka Russia Nat Village Kotzebue POB 296 Kotzebue AK 99752 USA Univ Washington Joint Inst Study Atmosphere & Ocean Seattle WA 98105 USA Alaska Beluga Whale Comm POB 306 Nome AK 99762 USA
We collated available satellite telemetry data for six species of ice-associated marine Mammals in the Pacific Arctic: ringed seals (Pusa hispida; n = 118), bearded seals (Erignathus barbatus, n = 51), spotted seals (... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... EBSCOASC期刊 EBSCOASC期刊 ebsco(ASP/aph) 评论
Comparing compressed sequences for faster nucleotide BLAST searches
收藏 引用
IEEE/ACM Transactions on Computational Biology and Bioinformatics 2007年 第3期4卷 349-364页
作者: Cameron, Michael Williams, Hugh E. RMIT Univ Sch Comp Sci & Informat Technol Melbourne Vic 3001 Australia Microsoft Corp Redmond WA 98052 USA
Molecular biologists, geneticists, and other life scientists use the BLAST homology search package as their first step for discovery of information about unknown or poorly annotated genomic sequences. There are two ma... 详细信息
来源: IEEE期刊 IEEE期刊 acm外刊 acm外刊 评论
Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors
收藏 引用
Journal of Biological Chemistry 2013年 第51期288卷 36703-36716页
作者: Zhou, Lei Lovell, Kimberly M. Frankowski, Kevin J. Slauson, Stephen R. Phillips, Angela M. Streicher, John M. Stahl, Edward Schmid, Cullen L. Hodder, Peter Madoux, Franck Cameron, Michael D. Prisinzano, Thomas E. Aube, Jeffrey Bohn, Laura M. Scripps Res Inst Dept Mol Therapeut & Neurosci Jupiter FL 33458 USA Scripps Res Inst Dept Lead Identificat Jupiter FL 33458 USA Univ Kansas Dept Med Chem Lawrence KS 66047 USA
Background: Kappa opioid receptor (KOR) signaling may produce antinociception through G protein or dysphoria through arrestin pathways. Results: Two highly selective, brain penetrant agonist scaffolds bias KOR signali... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... EBSCOASC期刊 EBSCOASC期刊 ebsco(MEDLINE/cmedm) ebsco(ASP/aph) 评论
Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)
收藏 引用
Journal of Medicinal Chemistry 2019年 第4期62卷 1761-1780页
作者: Guerrero, Miguel Urbano, Mariangela Kim, Eun-Kyong Gamo, Ana M. Riley, Sean Abgaryan, Lusine Leaf, Nora Van Orden, Lori Jean Brown, Steven J. Xie, Jennifer Y. Porreca, Frank Cameron, Michael D. Rosen, Hugh Roberts, Edward Scripps Res Inst Dept Mol Med 10550 North Torrey Pines Rd La Jolla CA 92037 USA BlackThorn Therapeut Inc 780 Brannan St San Francisco CA 94103 USA Univ Arizona Dept Pharmacol Tucson AZ 85724 USA Scripps Res Inst Dept Mol Med Jupiter FL 33458 USA Arkansas State Univ Coll Osteopath Med New York Inst Technol Dept Basic Sci Jonesboro AR 72446 USA
kappa opioid receptor (KOR) antagonists are potential pharmacotherapies for the treatment of migraine and stress-related mood disorders including depression, anxiety, and drug abuse, thus the development of novel KOR ... 详细信息
来源: ACS期刊 ebsco(MEDLINE/cmedm) 评论
Rational Development of 4-Aminopyridyl-Based Inhibitors Targeting Trypanosoma cruzi CYP51 as Anti-Chagas Agents
收藏 引用
Journal of Medicinal Chemistry 2013年 第19期56卷 7651-7668页
作者: Choi, Jun Yong Calvet, Claudia M. Gunatilleke, Shamila S. Ruiz, Claudia Cameron, Michael D. McKerrow, James H. Podust, Larissa M. Roush, William R. Scripps Florida Dept Chem Jupiter FL 33458 USA Scripps Florida Dept Mol Therapeut Jupiter FL 33458 USA Univ Calif San Francisco Ctr Discovery & Innovat Parasit Dis San Francisco CA 94158 USA Univ Calif San Francisco Dept Pathol San Francisco CA 94158 USA
A new series of 4-aminopyridyl-based lead inhibitors targeting Trypanosoma cruzi CYP51 (TcCYP51) has been developed using structure-based drug design as well as structure-property relationship (SPR) analyses. The scre... 详细信息
来源: ACS期刊 ebsco(MEDLINE/cmedm) 评论
In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin
收藏 引用
Bioorganic and medicinal chemistry 2017年 第6期25卷 1990-1996页
作者: Dong, Liao-Bin Rudolf, Jeffrey D. Lin, Li Ruiz, Claudia Cameron, Michael D. Shen, Ben Scripps Res Inst Dept Chem 130 Scripps Way Jupiter FL 33458 USA Scripps Res Inst Dept Mol Med 130 Scripps Way Jupiter FL 33458 USA Scripps Res Inst Nat Prod Lib Initiat 130 Scripps Way Jupiter FL 33458 USA
Platensimycin (PTM) and platencin (PTN), two natural products and promising drug leads that target bacterial and mammalian fatty acid synthases, are known to have unfavorable pharmacokinetic properties. It is not clea... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... EBSCOASC期刊 EBSCOASC期刊 ebsco(ASP/aph) ebsco(MEDLINE/cmedm) 评论
Development of highly selective casein kinase 1 delta/1 epsilon (CK1 delta/epsilon) inhibitors with potent antiproliferative properties
收藏 引用
Bioorganic and Medicinal Chemistry Letters 2013年 第15期23卷 4374-4380页
作者: Bibian, Mathieu Rahaim, Ronald J. Choi, Jun Yong Noguchi, Yoshihiko Schuerer, Stephan Chen, Weimin Nakanishi, Shima Licht, Konstantin Rosenberg, Laura H. Li, Lin Feng, Yangbo Cameron, Michael D. Duckett, Derek R. Cleveland, John L. Roush, William R. Scripps Florida Dept Chem Jupiter FL 33458 USA Scripps Florida Dept Canc Biol Jupiter FL 33458 USA Scripps Florida Dept Mol Therapeut Jupiter FL 33458 USA Univ Miami Dept Mol & Cellular Pharmacol Miami FL 33136 USA Univ Miami Ctr Computat Sci Miami FL 33136 USA
The development of a series of potent and highly selective casein kinase 1 delta/epsilon (CK1 delta/epsilon) inhibitors is described. Starting from a purine scaffold inhibitor (SR-653234) identified by high throughput... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... EBSCOASC期刊 EBSCOASC期刊 ebsco(ASP/aph) 评论